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Drug tests are required in many scenarios. You need to pass one before employment while random tests are mostly provided by employers. You may be asked to take a drug test during probation, DUI charges, and child custody.


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Try out PMC Labs and tell us what you think. Learn More. Niacin is a form of vitamin B3 which is used for the medical treatment of hyperlipidemia and niacin deficiency. However, within the last few years, it is being advertised on the Internet as a quick way to detoxify the Massage in providence ri body in an attempt to evade urine drug tests. This claim is without any medical or scientific evidence and as a result, many cases have been reported where young adults have ended up with niacin toxicity.

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To report a case of hepatotoxicity when niacin was used by a patient with HIV to pass a drug test.

Niacin is a soluble pyridine derivative widely used in the management of dyslipidemia. Common adverse effects include flushing, nausea, gastrointestinal discomfort, and hepatotoxicity. The use of niacin for nonmedical purposes has been increasing in prevalence in recent years, particularly in attempts to alter or mask of urine drug tests.

Although there is no scientific evidence that niacin can alter a urine drug screen result, easily retrievable information exists on the Internet touting niacin as a Free uk dating completely free dating way to prevent detection of tetrahydrocannabinol THC. The following report describes a case of hepatotoxicity in an HIV-infected adult who reported using niacin to mask THC in urine drug screen. The patient developed marked elevations in his liver enzymes aspartate aminotransferase greater than 25 times the upper limit of normal and alanine aminotransferase greater than 3 times the upper limit of normal that resolved after discontinuation of the drug.

The patient did not develop further clinical abnormalities proposed to be secondary to niacin toxicity in ly published case reports, including glucose abnormalities, coagulopathies, metabolic acidosis, QTc Tonight sex in Gainesville, and myalgias.

Health care providers should be aware of this nonmedical use of niacin to alter or mask a drug test, especially when discerning the cause of hepatotoxicity. In addition, pharmacists in the community setting should be aware of this use of niacin when encountering patients purchasing over-the-counter niacin, particularly in patients who may be more likely to use illicit substances.

Spencer H. Elizabeth W. Kimberley J. Disclosure: The authors declare no conflicts of interest or financial interests in any product or service mentioned in this article.

View PDF. Access through your institution Purchase PDF. Science and Practice Case Report. Author links open overlay panel Spencer H. Durham Elizabeth W. Covington Kimberley J. Add to Mendeley Share.

Abstract Objectives To report a case of hepatotoxicity when niacin was used by a patient with HIV to pass a drug test. Methods Should i date him is a soluble pyridine derivative widely used in the management of dyslipidemia. Conclusion Health care providers should be aware of this nonmedical use of niacin to alter or mask a drug test, especially when discerning the cause of hepatotoxicity.

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